Search results for "primary [cosmic radiation]"
showing 10 items of 1110 documents
Chronic Spontaneous Urticaria in Patients with Common Variable Immunodeficiency
2018
Common variable immunodeficiency (CVID) is a predominantly antibody deficiency and is one of the most common primary immunodeficiencies in adulthood. Replacement therapy with Ig has significantly reduced infectious complications; however, malignant, autoimmune, and inflammatory diseases are still current major causes of morbidity and mortality. In recent years, interest has increased regarding allergic manifestations that may be associated with primary immunodeficiencies; however, no data are currently available on chronic spontaneous urticaria (CSU). In this report, the authors describe CSU in patients with CVID attending their centre. Three CVID patients were affected by CSU and were unre…
The hedgehog receptor patched is involved in cholesterol transport.
2011
International audience; BACKGROUND: Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors, and one of the most affected Shh signaling steps found in these tumors is the regulation of the signaling receptor Smoothened by the Shh receptor Patched. In the present work, we investigated Patched activity and the mechanism by which Patched inhibits Smoothened. METHODOLOGY/PRINCIPAL FINDINGS: Using the well-known Shh-responding cell line of mouse fibroblasts NIH 3T3, we first observed that enhancement …
Finnish teachers as civic educators : From vision to action
2020
In this article, we examine Finnish class teachers as citizenship educators. Over the last ten years, the autonomous position of the Finnish teacher has become a symbol of the world-famous education system, and this study aims to illustrate how this freedom comes true in the framework of teacher as a citizenship educator. A prior study shows that teachers mostly share the same universal values, emphasizing altruism rather than individualism. Socially, teachers are more focused on maintaining the status quo and continuity of society than changing it radically. This article aims to answer the question how teachers define their role between society and individual learners and how they prioriti…
Flipped learning e gioia del lavoro ben fatto. Una ricerca con i futuri docenti di scuola primaria e dell'infanzia
2019
La formazione iniziale degli insegnanti richiede un approccio sistemico e modelli formativi per la promozione di interventi finalizzati a favorire negli studenti la consapevolezza del valore dello studio in un quadro orientato a favorire i risultati della formazione così come definiti dai Descrittori di Dublino e a sostenere l'apprendimento responsabile dello studente. La promozione della qualità della didattica universitaria ha come scopo fondamentale quello di garantire agli studenti un apprendimento significativo ed efficace. Initial teacher training requires a systemic approach and training models for the promotion of interventions aimed at encouraging students to evaluate the value of …
Networked Analysis of a Teaching Unit for Primary School Symmetries in the Form of an E-Book
2021
In mathematics education, technology offers many opportunities to enrich curricular contents. Plane symmetries is a topic often skipped by primary teachers. However, it is important and may be worked in attractive ways in dynamic geometry software environments. In any regular classroom there are students with different levels of mathematical attainment, some needing easy tasks while others, particularly mathematically-gifted students, need challenging problems. We present a teaching unit for plane symmetries, adequate for upper primary school grades, implemented in a fully interactive electronic book, with most activities solved in GeoGebra apps. The book allows student to choose which itin…
Skolēnu izziņas intereses sekmēšana matemātikas mācībā 1. klasē
2018
Bakalaura darba tēma ir: “Skolēnu izziņas intereses sekmēšana matemātikas mācībā 1.klasē”. Mūsdienās skolēnu izziņas intereses sekmēšanai ir ļoti svarīga nozīmē mācības, skolotājam jāpanāk, lai skolēniem būtu interese un vēlme mācīties. Pētījuma objekts: Matemātikas apguves process sākumskolā Pētījuma priekšmets: Izziņas intereses sekmēšana Pētījuma mērķis: Izpētīt izziņas intereses veicināšanas iespējas matemātikas mācībā 1.klasē. Bakalaura darbs tiek izstrādāts kas jādara, lai skolēniem būtu vairāk intereses matemātikas mācību priekšmeta apguve. Tēma ir aktuāla īpaši 1.klases skolēniem, šajā vecumposma formējas ieinteresētībā, izziņas interese attīsta skolēniem uzmanību, gribu koncentrēša…
Child-Centered and Teacher-Directed Practices in Two Different Countries: A Descriptive Case Study in Finnish and Japanese Grade 1 Classrooms
2023
This descriptive case study examined how teaching practices were evidenced in Grade 1 classrooms in two different cultural and educational contexts, Finland and Japan. Teachers’ teaching practices were video-recorded in 53 classrooms in Finland and six classrooms in Japan and rated with the Early Childhood Classroom Observation Measure by trained investigators. Four Finnish teachers and two Japanese teachers having the highest scores in either child-centered or teacher-directed practices were selected for a descriptive case study to take a closer look at how teaching practices in terms of management, climate, and instruction are evidenced in authentic classroom situations. The analysis reve…
Cuba and Italy: a comparative study on the determinants of health in a context of limited resources
2012
Italian and Cuban healthcare systems, although operating in very different context, show some of the best evidence in the world in terms of health outcomes. The Cuban model, unique because of an historical-economic-political asset not repeatable, had oriented its development on education and health promotion through a public health approach. The aim of our study is to perform a comparison of the Italian and Cuban healthcare system through the use of health indicators validated at international level in order to identify best practices. Cuba provides health care to all residents focusing strongly on primary care and health promotion and obtains similar results to Italy despite the limited av…
Children's exploration of the concepts of home and belonging: Capturing views from five European countries.
2021
Understanding one's sense of belonging is a central part of identity formation and self-awareness; feeling safe somewhere, with specific people is identified as a basic human need. This paper explores the ideas of children from three age groups in five different European as they discussed the concepts of ‘home’ and ‘belonging’. Findings showed that the children's ideas could be organised into six interrelated aspects: Spatiality, Materiality, Multiplicity, Social Relations, Affect, and Dislocation. Whilst there were differences in the ways that the children conceptualised home across the classes, even the youngest children were able to describe their ideas using metaphors and abstract conce…